Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastase

Copyright © 2016 by the American Thoracic Society. Neutrophil elastase (NE) activity is associated with many destructive lung diseases and is a predictor for structural lung damage in early cystic fibrosis (CF), which suggests normal maintenance of airway epitheliumis prevented byuninhibitedNE.Howev...

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Bibliographic Details
Main Authors: Garratt, L.W., Sutanto, E.N., Ling, K.M., Looi, K., Iosifidis, T., Martinovich, K.M., Shaw, N.C., Buckley, A.G., Kicic-Starcevich, E., Lannigan, F.J., Knight, D.A., Stick, S.M., Kicic, Anthony
Format: Journal Article
Language:English
Published: AMER THORACIC SOC 2016
Subjects:
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Cell Biology
Respiratory System
neutrophil elastase
cystic fibrosis
primary cell culture
wound repair
alpha-1 antitrypsin
CYSTIC-FIBROSIS PATIENTS
YOUNG-CHILDREN
LUNG-DISEASE
MORPHOLOGICAL-CHANGES
GENE-EXPRESSION
CIGARETTE-SMOKE
WOUND REPAIR
IN-VITRO
INTERLEUKIN-8
INFLAMMATION
Online Access:http://hdl.handle.net/20.500.11937/76814

Internet

http://hdl.handle.net/20.500.11937/76814

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