Persistent induction of goblet cell differentiation in the airways: Therapeutic approaches

Persistent induction of goblet cell differentiation in the airways: Therapeutic approaches

© 2017 Dysregulated induction of goblet cell differentiation results in excessive production and retention of mucus and is a common feature of several chronic airways diseases. To date, therapeutic strategies to reduce mucus accumulation have focused primarily on altering the properties of the mucus...

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Bibliographic Details
Main Authors: Reid, A.T., Veerati, P.C., Gosens, R., Bartlett, N.W., Wark, P.A., Grainge, C.L., Stick, S.M., Kicic, Anthony, Moheimani, F., Hansbro, P.M., Knight, D.A.
Format: Journal Article
Language:English
Published: PERGAMON-ELSEVIER SCIENCE LTD 2018
Subjects:
Science & Technology
Life Sciences & Biomedicine
Pharmacology & Pharmacy
Goblet cell
Asthma
COPD
Cystic fibrosis
Mucus
Epithelium
Signaling pathways
Therapeutic
micro-RNA
Mechanical stress
Monoclonal antibody therapy
GROWTH-FACTOR RECEPTOR
BRONCHIAL EPITHELIAL-CELLS
RECOMBINANT HUMAN INTERLEUKIN-5
OBSTRUCTIVE PULMONARY-DISEASE
RESPIRATORY SYNCYTIAL VIRUS
COLONY-STIMULATING FACTOR
CYSTIC-FIBROSIS
MUCUS OVERPRODUCTION
NEBULIZED AMILORIDE
MUCIN PRODUCTION
Online Access:http://hdl.handle.net/20.500.11937/76808

Internet

http://hdl.handle.net/20.500.11937/76808

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