Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

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Human Primary Epithelial Cell Models: Promising Tools in the Era of Cystic Fibrosis Personalized Medicine

Cystic fibrosis (CF) is an inherited disorder where individual disease etiology and response to therapeutic intervention is impacted by CF transmembrane regulator (CFTR) mutations and other genetic modifiers. CFTR regulates multiple mechanisms in a diverse range of epithelial tissues. In this Review...

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Bibliographic Details
Main Authors:	Awatade, N., Wong, S., Hewson, C., Fawcett, L., Kicic, Anthony, Jaffe, A., Waters, S.
Format:	Journal Article
Language:	English
Published:	FRONTIERS MEDIA SA 2018
Subjects:	Science & Technology Life Sciences & Biomedicine Pharmacology & Pharmacy cystic fibrosis organoid personalized medicine CFTR drug development sweat chloride CFTR modulator INTESTINAL CURRENT MEASUREMENT IN-VITRO CFTR POTENTIATOR TEZACAFTOR-IVACAFTOR ION-TRANSPORT REGENERATION LUMACAFTOR ABSORPTION CORRECTORS SPHEROIDS
Online Access:	http://hdl.handle.net/20.500.11937/76772

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