CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy

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CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy

© 2019, © 2019 The Author(s). Published with license by Taylor & Francis Group, LLC. Increasing life expectancy is associated with increased cancer incidence, yet the effect of cancer and anti-cancer treatment on elderly patients and their immune systems is not well understood. Declining T cel...

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Bibliographic Details
Main Authors:	Jackaman, Connie, Gardner, J., Tomay, F., Spowart, J., Crabb, Hannah, Dye, Danielle, Fox, Simon, Proksch, Stephen, Metharom, Pat, Dhaliwal, S., Nelson, Delia
Format:	Journal Article
Published:	Landes Bioscience 2019
Online Access:	http://hdl.handle.net/20.500.11937/74358

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