CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy
© 2019, © 2019 The Author(s). Published with license by Taylor & Francis Group, LLC. Increasing life expectancy is associated with increased cancer incidence, yet the effect of cancer and anti-cancer treatment on elderly patients and their immune systems is not well understood. Declining T cel...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Landes Bioscience
2019
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| Online Access: | http://hdl.handle.net/20.500.11937/74358 |