Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

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Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

Most cancers emerge in the elderly, including lung cancer and mesothelioma, yet the elderly remain an underrepresented population in pre-clinical cancer studies and clinical trials. The immune system plays a critical role in the effectiveness of many anticancer therapies in young hosts via tumor-spe...

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Bibliographic Details
Main Authors:	Duong, L., Radley-Crabb, H., Gardner, J., Tomay, F., Dye, D., Grounds, M., Pixley, F., Nelson, Delia, Jackaman, Connie
Format:	Journal Article
Published:	2018
Online Access:	http://purl.org/au-research/grants/nhmrc/1100803 http://hdl.handle.net/20.500.11937/74350

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