Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia
Most cancers emerge in the elderly, including lung cancer and mesothelioma, yet the elderly remain an underrepresented population in pre-clinical cancer studies and clinical trials. The immune system plays a critical role in the effectiveness of many anticancer therapies in young hosts via tumor-spe...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
2018
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| Online Access: | http://purl.org/au-research/grants/nhmrc/1100803 http://hdl.handle.net/20.500.11937/74350 |