Method Protocols for Metabolic and Functional Analysis of the BRIN-BD11 ß-Cell Line: A Preclinical Model for Type 2 Diabetes

In type 2 diabetes, prolonged dysregulation of signalling and ß-cell metabolic control leads to ß-cell dysfunction, and is increasingly associated with abnormal metabolic states which disrupt normal cellular physiology. Utilization of appropriate ß-cell models enables a systematic approach to unders...

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Bibliographic Details
Main Authors: Rowlands, J., Walz, N., Rowles, J., Keane, Kevin, Carlessi, Rodrigo, Newsholme, P.
Format: Journal Article
Published: Humana Press 2019
Online Access:http://hdl.handle.net/20.500.11937/74054