Development and validation of a simple LC-MS/MS method for the simultaneous quantitative determination of trimethylamine-N-oxide and branched chain amino acids in human serum

Serum branched chain amino acids and trimethylamine-N-oxide are monitored as potential indicators of diabetes and cardiovascular health respectively. A rapid method for their simultaneous determination using liquid chromatography and tandem mass spectrometry is described here. Branched chain amino a...

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Bibliographic Details
Main Authors: Le, T., Shafaei, A., Genoni, A., Christophersen, Claus, Devine, A., Lo, J., Wall, P., Boyce, M.
Format: Journal Article
Published: Springer 2019
Online Access:http://hdl.handle.net/20.500.11937/73913