Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma

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Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma

Background: Chemotherapeutic resistance of glioblastoma has been attributed to a self-renewing subpopulation, the glioma stem cells (GSCs), which is known to be maintained by the Wnt β−catenin pathway. Our previous findings demonstrated that exogeneous addition of the Wnt antagonist, secreted fizzle...

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Bibliographic Details
Main Authors:	Bhuvanalakshmi, G., Gamit, N., Patil, M., Arfuso, Frank, Sethi, G., Dharmarajan, Arunasalam, Kumar, A., Warrier, S.
Format:	Journal Article
Published:	MDPI AG 2019
Online Access:	http://hdl.handle.net/20.500.11937/73859

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