Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma
Background: Chemotherapeutic resistance of glioblastoma has been attributed to a self-renewing subpopulation, the glioma stem cells (GSCs), which is known to be maintained by the Wnt β−catenin pathway. Our previous findings demonstrated that exogeneous addition of the Wnt antagonist, secreted fizzle...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
MDPI AG
2019
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| Online Access: | http://hdl.handle.net/20.500.11937/73859 |