Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from Mozambique.

Despite effective measles vaccines, measles still causes severe morbidity and mortality worldwide, particularly in developing countries. The Th2 pathway involving interleukin (IL)-4 and IL-13 cytokines, and their receptor IL-4Ra, play important roles in the Th1/Th2 balance and antibody production. A...

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Bibliographic Details
Main Authors: Clifford, H., Hayden, C., Khoo, S., Naniche, D., Mandomando, I., Zhang, Guicheng, Richmond, P., Le Souëf, P.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/72943