PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells

© 2015 Wiley Publishing Asia Pty Ltd. Colon cancer is one of the most common cancers worldwide with high mortality. A major issue in colon cancer treatment is drug-resistance and metastasis that have been ascribed to the cancer stem cells. In this study, colon cancer stem cells were isolated through...

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Bibliographic Details
Main Authors: Chen, J., Shao, R., Li, F., Monteiro, M., Liu, Jian, Xu, Z., Gu, W.
Format: Journal Article
Published: Wiley-Blackwell Publishing Asia 2015
Online Access:http://hdl.handle.net/20.500.11937/72938