Preparation of silybin/poly(vinylpyrrolidone) nanodrugs by using the aerosol solvent extraction system for improving drug solubility

Silybin (SLB), a kind of antihepatotoxic polyphenolic substance, is currently available for a variety of acute and chronic liver diseases. However, its poor solubility and low bioavailability have strongly limited its therapeutic applications. In this work, we demonstrate a simple solution to addres...

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Bibliographic Details
Main Authors: Teng, W., Wang, J., Foster, Neil, Wen, N., Zhang, J.
Format: Journal Article
Published: American Chemical Society 2014
Online Access:http://hdl.handle.net/20.500.11937/72404