Effects of maturation and size on population pharmacokinetics of pentoxifylline and its metabolites in very preterm infants with suspected late-onset sepsis or necrotizing enterocolitis: a pilot study incorporating clinical outcomes

© 2018 The British Pharmacological Society Aims: Infection-induced inflammation is associated with adverse long-term outcomes in preterm infants. Pentoxifylline (PTX) is a candidate for adjunct immunomodulatory therapy in preterm infants with late-onset sepsis (LOS) and necrotizing enterocolitis (NE...

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Bibliographic Details
Main Authors: Salman, S., Hibbert, J., Page-Sharp, Madhu, Manning, L., Simmer, K., Doherty, D., Patole, S., Batty, Kevin, Strunk, T.
Format: Journal Article
Published: Wiley-Blackwell Publishing Ltd. 2018
Online Access:http://hdl.handle.net/20.500.11937/72063