Pharmacological effects of nanoencapsulation of human-based dosing of probucol on ratio of secondary to primary bile acids in gut, during induction and progression of type 1 diabetes

INTRODUCTION: The ratio of secondary to primary bile acids changes during Type 1 Diabetes (T1D) development and these effects might be ameliorated by using cholesterol lowering drugs or hydrophilic bile acids. Probucol is a cholesterol-lowering drug, while ursodeoxycholic acid is a hydrophilic bile...

Full description

Bibliographic Details
Main Authors: Mooranian, Armin, Zamani, Nassim, Takechi, Ryu, Al-Sallami, H., Mikov, M., Golocorbin-Kon, S., Kovacevic, B., Arfuso, Frank, Al-Salami, Hani
Format: Journal Article
Published: Taylor & Francis Inc. 2018
Online Access:http://hdl.handle.net/20.500.11937/72017