Characterisation of the structure and oligomerisation of islet amyloid polypeptides (IAPP): A review of molecular dynamics simulation studies

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Characterisation of the structure and oligomerisation of islet amyloid polypeptides (IAPP): A review of molecular dynamics simulation studies

Human islet amyloid polypeptide (hIAPP) is a naturally occurring, intrinsically disordered protein whose abnormal aggregation into amyloid fibrils is a pathological feature in type 2 diabetes, and its cross-aggregation with amyloid beta has been linked to an increased risk of Alzheimer’s disease. Th...

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Bibliographic Details
Main Authors:	Moore, S., Sonar, K., Bharadwaj, Prashant, Deplazes, Evelyne, Mancera, Ricardo
Format:	Journal Article
Published:	M D P I AG 2018
Online Access:	http://hdl.handle.net/20.500.11937/71838

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