Characterisation of the structure and oligomerisation of islet amyloid polypeptides (IAPP): A review of molecular dynamics simulation studies
Human islet amyloid polypeptide (hIAPP) is a naturally occurring, intrinsically disordered protein whose abnormal aggregation into amyloid fibrils is a pathological feature in type 2 diabetes, and its cross-aggregation with amyloid beta has been linked to an increased risk of Alzheimer’s disease. Th...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal Article |
| Published: |
M D P I AG
2018
|
| Online Access: | http://hdl.handle.net/20.500.11937/71838 |