Environmental enrichment intervention for Rett syndrome: An individually randomised stepped wedge trial
Background: Rett syndrome is caused by a pathogenic mutation in the MECP2 gene with major consequences for motor and cognitive development. One of the effects of impaired MECP2 function is reduced production of Brain Derived Neurotrophic Factor (BDNF), a protein required for normal neuronal developm...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
BioMed Central Ltd.
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/71624 |