Morphological, Stability, and Hypoglycemic Effects of New Gliclazide-Bile Acid Microcapsules for Type 1 Diabetes Treatment: the Microencapsulation of Anti-diabetics Using a Microcapsule-Stabilizing Bile Acid

© 2018, American Association of Pharmaceutical Scientists. When we administered orally a mixture of the anti-diabetic drug, gliclazide (G) and a primary bile acid, they exerted a hypoglycemic effect in a rat model of type 1 diabetes (T1D), but stability of mixture was limited. We aimed to develop an...

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Bibliographic Details
Main Authors: Mathavan, S., Chen-Tan, N., Arfuso, Frank, Al-Salami, Hani
Format: Journal Article
Published: AAPS 2018
Online Access:http://hdl.handle.net/20.500.11937/71494