Iron chelators for the treatment of cancer

The study of iron chelators as anti-tumor agents is still in its infancy. Iron is important for cellular proliferation and this is demonstrated by observations that iron-depletion results in cell cycle arrest and also apoptosis. In addition, many iron chelators are known to inhibit ribonucleotide re...

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Bibliographic Details
Main Authors: Yu, Yu, Gutierrez, E., Kovacevic, Z., Saletta, F., Obeidy, P., Rahmanto, Y., Richardson, D.
Format: Journal Article
Published: Bentham Science Publishers 2012
Online Access:http://hdl.handle.net/20.500.11937/7118