Synthesis of 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides and their tautomerism

Two complementary pathways for the preparation of N-substituted 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides (5) were proposed and successfully realized in the synthesis of 20 representative examples. These methods use the same types of starting materials viz. succinic anhydride, aminoguanidine hyd...

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Bibliographic Details
Main Authors: Lim, F., Tan, L., Tiekink, E., Dolzhenko, Anton
Format: Journal Article
Published: Royal Society of Chemistry 2018
Online Access:http://hdl.handle.net/20.500.11937/69766