Extracellular matrix (ECM) activates β-catenin signaling in uterine fibroids

Recent studies showed that genetic aberrations in the MED12 gene, probably through the canonical WNT/β-catenin pathway, lead to the pathogenesis of uterine fibroids. However, a comprehensive analysis of the WNT pathway in MED12-mutated and MED12-wild-type fibroids has not been performed. The objecti...

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Bibliographic Details
Main Authors: Ko, Y., Jamaluddin, M., Adebayo, M., Bajwa, P., Scott, R., Dharmarajan, Arunasalam, Nahar, P., Tanwar, P.
Format: Journal Article
Published: BioScientifica Ltd. 2018
Online Access:http://hdl.handle.net/20.500.11937/68225