Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China
Diet has been shown to have an effect on both inflammation and oesophageal cancer. This study investigated the association between the dietary inflammatory index (DII ® ) and the risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China. A case–control study was conducted during 2008–20...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal Article |
| Published: |
Cambridge University Press
2018
|
| Online Access: | http://hdl.handle.net/20.500.11937/67808 |
| _version_ | 1848761663469125632 |
|---|---|
| author | Tang, L. Shivappa, N. Hebert, J. Lee, A. Xu, F. Binns, Colin |
| author_facet | Tang, L. Shivappa, N. Hebert, J. Lee, A. Xu, F. Binns, Colin |
| author_sort | Tang, L. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Diet has been shown to have an effect on both inflammation and oesophageal cancer. This study investigated the association between the dietary inflammatory index (DII ® ) and the risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China. A case–control study was conducted during 2008–2009 in Urumqi and Shihezi. DII scores were calculated based on dietary intake assessed by a validated FFQ administered to 359 incident oesophageal cancer patients and 380 hospital-based controls. Higher DII scores indicate more pro-inflammatory diets. Logistic regression analyses were performed to assess the association between DII scores and oesophageal cancer risk. Oesophageal cancer patients had a significantly higher median DII score (-0·35; interquartile range (IQR)=-2·25, 1·86) than that of controls (-1·41; IQR -3·07, 0·40). Multivariable logistic analysis revealed a positive association between higher DII scores and oesophageal cancer risk (OR Quartile 4 v. 1 2·55; 95 % CI 1·61, 4·06; P trend < 0·001). A pro-inflammatory diet appears to be associated with an increased risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region. Specific carcinogenic mechanisms are discussed. Accumulating evidence, to which the study contributes, indicates that encouraging the intake of more anti-inflammatory foods may be a strategy to protect against oesophageal cancer in this high-risk area of China. |
| first_indexed | 2025-11-14T10:35:15Z |
| format | Journal Article |
| id | curtin-20.500.11937-67808 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T10:35:15Z |
| publishDate | 2018 |
| publisher | Cambridge University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-678082018-08-09T06:46:44Z Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China Tang, L. Shivappa, N. Hebert, J. Lee, A. Xu, F. Binns, Colin Diet has been shown to have an effect on both inflammation and oesophageal cancer. This study investigated the association between the dietary inflammatory index (DII ® ) and the risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China. A case–control study was conducted during 2008–2009 in Urumqi and Shihezi. DII scores were calculated based on dietary intake assessed by a validated FFQ administered to 359 incident oesophageal cancer patients and 380 hospital-based controls. Higher DII scores indicate more pro-inflammatory diets. Logistic regression analyses were performed to assess the association between DII scores and oesophageal cancer risk. Oesophageal cancer patients had a significantly higher median DII score (-0·35; interquartile range (IQR)=-2·25, 1·86) than that of controls (-1·41; IQR -3·07, 0·40). Multivariable logistic analysis revealed a positive association between higher DII scores and oesophageal cancer risk (OR Quartile 4 v. 1 2·55; 95 % CI 1·61, 4·06; P trend < 0·001). A pro-inflammatory diet appears to be associated with an increased risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region. Specific carcinogenic mechanisms are discussed. Accumulating evidence, to which the study contributes, indicates that encouraging the intake of more anti-inflammatory foods may be a strategy to protect against oesophageal cancer in this high-risk area of China. 2018 Journal Article http://hdl.handle.net/20.500.11937/67808 10.1017/S0007114518000405 Cambridge University Press restricted |
| spellingShingle | Tang, L. Shivappa, N. Hebert, J. Lee, A. Xu, F. Binns, Colin Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China |
| title | Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China |
| title_full | Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China |
| title_fullStr | Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China |
| title_full_unstemmed | Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China |
| title_short | Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China |
| title_sort | dietary inflammatory index and risk of oesophageal cancer in xinjiang uyghur autonomous region, china |
| url | http://hdl.handle.net/20.500.11937/67808 |