Whole genome sequencing of 91 multiplex schizophrenia families reveals increased burden of rare, exonic copy number variation in schizophrenia probands and genetic heterogeneity

Whole genome sequencing of 91 multiplex schizophrenia families reveals increased burden of rare, exonic copy number variation in schizophrenia probands and genetic heterogeneity

The importance of genomic copy number variants (CNVs) has long been recognized in the etiology of neurodevelopmental diseases. We report here the results from the CNV analysis of whole-genome sequences from 91 multiplex schizophrenia families. Employing four algorithms (CNVnator, Cn.mops, DELLY and...

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Bibliographic Details
Main Authors: Khan, F., Melton, Phillip, McCarthy, N., Morar, B., Blangero, J., Moses, Eric, Jablensky, A.
Format: Journal Article
Published: 2018
Online Access:http://hdl.handle.net/20.500.11937/67053

Internet

http://hdl.handle.net/20.500.11937/67053

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