Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base

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Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base

Ellis-van Creveld syndrome protein homolog (Evc) was previously shown to mediate expression of Indian hedgehog (Ihh) downstream targets in chondrocytes. Consequently disruption of the Ihh/Pthrp axis was demonstrated in Evc -/- mice, but the full extent of Evc involvement in endochondral development...

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Bibliographic Details
Main Authors:	Pacheco, M., Valencia, M., Caparrós-Martín, Jose, Mulero, F., Goodship, J., Ruiz-Perez, V.
Format:	Journal Article
Published:	Elsevier Science 2012
Online Access:	http://hdl.handle.net/20.500.11937/66971

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