Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base
Ellis-van Creveld syndrome protein homolog (Evc) was previously shown to mediate expression of Indian hedgehog (Ihh) downstream targets in chondrocytes. Consequently disruption of the Ihh/Pthrp axis was demonstrated in Evc -/- mice, but the full extent of Evc involvement in endochondral development...
| Main Authors: | , , , , , |
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| Format: | Journal Article |
| Published: |
Elsevier Science
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/66971 |