Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast

Background: Genome mining facilitated by heterologous systems is an emerging approach to access the chemical diversity encoded in basidiomycete genomes. In this study, three sesquiterpene synthase genes, GME3634, GME3638, and GME9210, which were highly expressed in the sclerotium of the medicinal mu...

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Bibliographic Details
Main Authors: Yap, H., Muria Gonzalez, Jordi, Kong, B., Stubbs, K., Tan, C., Ng, S., Tan, N., Solomon, P., Fung, S., Chooi, Y.
Format: Journal Article
Published: 2017
Online Access:http://hdl.handle.net/20.500.11937/66958