A model-based control scheme for depth of hypnosis in anesthesia

© 2018 Elsevier Ltd. In this paper we propose a model-based scheme to control the depth of hypnosis in anesthesia that uses the BIS signal as controlled variable. In particular, the control scheme exploits the propofol pharmacokinetics/pharmacodynamics model of the patient so that the estimated effe...

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Bibliographic Details
Main Authors: Merigo, L., Padula, Fabrizio, Pawlowski, A., Dormido, S., Guzmán Sánchez, J., Latronico, N., Paltenghi, M., Visioli, A.
Format: Journal Article
Published: 2018
Online Access:http://hdl.handle.net/20.500.11937/66178