Insulin and IGF-1 receptor autocrine loops are not required for Exendin-4 induced changes to pancreatic ß-cell bioenergetic parameters and metabolism in BRIN-BD11 cells
Pharmacological long lasting Glucagon-like peptide-1 (GLP-1) analogues, such as Exendin-4, have become widely used diabetes therapies. Chronic GLP-1R stimulation has been linked to ß-cell protection and these pro-survival actions of GLP-1 are dependent on the activation of the mammalian target of ra...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
Elsevier
2018
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| Online Access: | http://hdl.handle.net/20.500.11937/65488 |