The Role of Secreted Frizzled-related Protein-4 (sFRP4) in the Epigenetics, Metabolism and Chemo-sensitisation of Cancer Stem Cells
This study investigated molecular signals involved in sustaining CSCs and ways to target their activity using sFRP4 alone or in combination with chemotherapeutic drugs, possible involvement of methylation-mediated silencing of the sFRP gene family, and metabolic reprogramming by relocating metabolic...
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| Format: | Thesis |
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Curtin University
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/65388 |