The Role of Drug Metabolites in the Inhibition of Cytochrome P450 Enzymes

© 2017, Springer International Publishing Switzerland. Following the drug administration, patients are exposed not only to the parent drug itself, but also to the metabolites generated by drug-metabolizing enzymes. The role of drug metabolites in cytochrome P450 (CYP) inhibition and subsequent drug–...

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Bibliographic Details
Main Authors: Mikov, M., Ðanic, M., Pavlovic, N., Stanimirov, B., Golocorbin-Kon, S., Stankov, K., Al-Salami, Hani
Format: Journal Article
Published: Springer France 2017
Online Access:http://hdl.handle.net/20.500.11937/63373