Synthesis of N-(5-chloro-6-(quinolin-3-yloxy)pyridin-3-yl) benzenesulfonamide derivatives as non-TZD peroxisome proliferator-activated receptor γ (PPARγ) agonist

Synthesis of N-(5-chloro-6-(quinolin-3-yloxy)pyridin-3-yl) benzenesulfonamide derivatives as non-TZD peroxisome proliferator-activated receptor γ (PPARγ) agonist

The thiazolidinediones (TZDs) are a class of oral antidiabetic drugs that improve insulin sensitivity in patients with type 2 diabetes. Although the mechanism by which the TZDs lower insulin resistance is unclear, they are known to target the peroxisome proliferator-activated receptor γ (PPARγ), a...

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Bibliographic Details
Main Authors: Bajare, S., Anthony, J., Nair, A., Marita, R., Damre, A., Patel, Dharmeshkumar, Rao, C., Sivaramakrishnan, H., Deka, N.
Format: Journal Article
Published: Elsevier Masson 2012
Online Access:http://hdl.handle.net/20.500.11937/63365

Internet

http://hdl.handle.net/20.500.11937/63365

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