Computational site-directed mutagenesis studies of the role of the hydrophobic triad on substrate binding in cholesterol oxidase
© 2017 Wiley Periodicals, Inc. Cholesterol oxidase (ChOx) is a flavoenzyme that oxidizes and isomerizes cholesterol (CHL) to form cholest-4-en-3-one. Molecular docking and molecular dynamics simulations were conducted to predict the binding interactions of CHL in the active site. Several key intera...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
John Wiley & Sons, Inc.
2017
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| Online Access: | http://hdl.handle.net/20.500.11937/63291 |