Secreted Frizzled-related protein 4 (sFRP4) chemo-sensitizes cancer stem cells derived from human breast, prostate, and ovary tumor cell lines

© 2017 The Author(s). This study investigated molecular signals essential to sustain cancer stem cells (CSCs) and assessed their activity in the presence of secreted frizzled-related protein 4 (sFRP4) alone or in combination with chemotherapeutic drugs. SFRP4 is a known Wnt antagonist, and is also p...

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Bibliographic Details
Main Authors: Deshmukh, A., Kumar, S., Arfuso, Frank, Newsholme, Philip, Dharmarajan, Arunasalam
Format: Journal Article
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/20.500.11937/63155