Design and synthesis of non-TZD peroxisome proliferator-activated receptor Î³ (PPARÎ³) modulator

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Design and synthesis of non-TZD peroxisome proliferator-activated receptor Î³ (PPARÎ³) modulator

Thiazolidinediones (TZDs) are an important class of compound used for the treatment of type 2 diabetes, targeting the peroxisome proliferator-activated receptor Î³ (PPARÎ³). Drug-induced hepatotoxicity, edema, and weight gain are the main concerns associated with TZDs. It was unclear whether the sid...

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Bibliographic Details
Main Authors:	Deka, N., Uravane, M., Anthony, J., Bhumra, S., Nair, A., B-Rao, C., Patel, Dharmeshkumar, Sivaramakrishnan, H.
Format:	Journal Article
Published:	Birkhaeuser Science 2014
Online Access:	http://hdl.handle.net/20.500.11937/63091

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