Design and synthesis of non-TZD peroxisome proliferator-activated receptor γ (PPARγ) modulator
Thiazolidinediones (TZDs) are an important class of compound used for the treatment of type 2 diabetes, targeting the peroxisome proliferator-activated receptor γ (PPARγ). Drug-induced hepatotoxicity, edema, and weight gain are the main concerns associated with TZDs. It was unclear whether the sid...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
Birkhaeuser Science
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/63091 |