HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay

Inheritance of HLA-B*5701 is a strong predictor of a hypersensitivity reaction to the anti-HIV drug abacavir. The identification of susceptible individuals prior to the institution of abacavir therapy is therefore of clinical importance and has generated demand for a simple and rapid diagnostic test...

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Bibliographic Details
Main Authors: Hammond, E., Cyril, Nolan, D., Mallal, S.
Format: Journal Article
Published: Blackwell Munksgaard 2007
Online Access:http://hdl.handle.net/20.500.11937/5945