High expression of connective tissue growth factor accelerates dissemination of leukaemia

To improve treatment of acute lymphoblastic leukaemia (ALL), a better understanding of disease development is needed to tailor new therapies. Connective tissue growth factor (CTGF/CCN2) is highly expressed in leukaemia cells from the majority of paediatric patients with B-lineage ALL (pre-B ALL). CT...

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Bibliographic Details
Main Authors: Wells, J., Howlett, M., Halse, H., Heng, J., Ford, J., Cheung, Laurence, Samuels, A., Crook, M., Charles, A., Cole, C., Kees, U.
Format: Journal Article
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/20.500.11937/59373