The effect of ovarian reserve and receptor signalling on granulosa cell apoptosis during human follicle development

The poor oocyte quality in older women has previously been linked to the depletion of the ovarian reserve of primordial follicles and an increase in granulosal apoptosis. Granulosa cells were collected from 198 follicles and individually analysed by flow cytometry. In the young IVF patients, the lev...

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Bibliographic Details
Main Authors: Regan, S., Knight, P., Yovich, John, Stanger, J., Leung, Y., Arfuso, Frank, Almahbobi, Ghanim, Dharmarajan, Arunasalam
Format: Journal Article
Published: Elsevier Ireland Ltd 2017
Online Access:http://hdl.handle.net/20.500.11937/59170