Early Proliferation Does Not Prevent the Loss of Oligodendrocyte Progenitor Cells during the Chronic Phase of Secondary Degeneration in a CNS White Matter Tract
Partial injury to the central nervous system (CNS) is exacerbated by additional loss of neurons and glia via toxic events known as secondary degeneration. Using partial transection of the rat optic nerve (ON) as a model, we have previously shown that myelin decompaction persists during secondary deg...
| Main Authors: | Payne, S., Bartlett, C., Savigni, D., Harvey, A., Dunlop, S., Fitzgerald, Melinda |
|---|---|
| Format: | Journal Article |
| Published: |
Public Library of Science
2013
|
| Online Access: | http://hdl.handle.net/20.500.11937/58953 |
Similar Items
Oxidative stress in oligodendrocytes in the penumbra following partial injury to a CNS tract and its amelioration with 670nm light
by: Szymanski, C., et al.
Published: (2012)
by: Szymanski, C., et al.
Published: (2012)
Myelin Sheath Decompaction, Axon Swelling, and Functional Loss during Chronic Secondary Degeneration in Rat Optic Nerve
by: Payne, S., et al.
Published: (2012)
by: Payne, S., et al.
Published: (2012)
Life, death, and oxidative stress: fate mapping oligodendrocyte progenitor cells following neurotrauma
by: Giacci, M., et al.
Published: (2015)
by: Giacci, M., et al.
Published: (2015)
PROTECTING GLIA FROM OXIDATIVE STRESS DURING SECONDARY DEGENERATION FOLLOWING NEUROTRAUMA
by: Doig, R., et al.
Published: (2014)
by: Doig, R., et al.
Published: (2014)
Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma
by: Savigni, D., et al.
Published: (2013)
by: Savigni, D., et al.
Published: (2013)
In vitro cytotoxicity assessment of ruxolitinib on oligodendrocyte precursor cell and neural stem/progenitor cell populations
by: Lim, Cheng-Wei, et al.
by: Lim, Cheng-Wei, et al.
In vitro cytotoxicity assessment of ruxolitinib on oligodendrocyte precursor cell and neural stem/progenitor cell populations
by: Lim, Cheng-Wei, et al.
Published: (2024)
by: Lim, Cheng-Wei, et al.
Published: (2024)
Changes to mitochondrial ultrastructure in optic nerve vulnerable to secondary degeneration in vivo are limited by irradiation at 670 nm
by: Cummins, N., et al.
Published: (2013)
by: Cummins, N., et al.
Published: (2013)
Vulnerability and fate of oligodendroglia in areas of secondary degeneration following neurotrauma
by: Giacci, M., et al.
Published: (2015)
by: Giacci, M., et al.
Published: (2015)
Paranode Abnormalities and Oxidative Stress in Optic Nerve Vulnerable to Secondary Degeneration: Modulation by 670 nm Light Treatment
by: Szymanski, C.R., et al.
Published: (2013)
by: Szymanski, C.R., et al.
Published: (2013)
Strategies to limit dysmyelination during secondary degeneration following neurotrauma
by: Fitzgerald, Melinda
Published: (2014)
by: Fitzgerald, Melinda
Published: (2014)
Evaluation of the "Cellscreen" system for proliferation studies on liver progenitor cells
by: Viebahn, C., et al.
Published: (2006)
by: Viebahn, C., et al.
Published: (2006)
Retinal genes are differentially expressed in areas of primary versus secondary degeneration following partial optic nerve injury
by: Chiha, W., et al.
Published: (2018)
by: Chiha, W., et al.
Published: (2018)
Reactive species and oxidative stress in optic nerve vulnerable to secondary degeneration
by: O'Hare Doig, R., et al.
Published: (2014)
by: O'Hare Doig, R., et al.
Published: (2014)
Comparison of ion channel inhibitor combinations for limiting secondary degeneration following partial optic nerve transection
by: Toomey, L., et al.
Published: (2018)
by: Toomey, L., et al.
Published: (2018)
Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma
by: O'Hare Doig, R., et al.
Published: (2017)
by: O'Hare Doig, R., et al.
Published: (2017)
Kinase targets in CNS drug discovery
by: Gunosewoyo, Hendra, et al.
Published: (2017)
by: Gunosewoyo, Hendra, et al.
Published: (2017)
Comparative assessment of phototherapy protocols for reduction of oxidative stress in partially transected spinal cord slices undergoing secondary degeneration
by: Ashworth, B., et al.
Published: (2016)
by: Ashworth, B., et al.
Published: (2016)
Delayed treatment of secondary degeneration following acute optic nerve transection using a combination of ion channel inhibitors
by: Yates, N., et al.
Published: (2017)
by: Yates, N., et al.
Published: (2017)
Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection
by: Toomey, Lilian, et al.
Published: (2019)
by: Toomey, Lilian, et al.
Published: (2019)
Characterisation of liver progenitor cells and their microenvironment during chronic liver disease and hepatocarcinogenesis
by: Köhn, Julia
Published: (2016)
by: Köhn, Julia
Published: (2016)
Functionally relevant white matter degradation in multiple sclerosis: a tract-based spatial meta-analysis
by: Welton, Thomas, et al.
Published: (2015)
by: Welton, Thomas, et al.
Published: (2015)
CLIPPERS the brain biter: An adolescent’s experience of a rare CNS disorder
by: Anuar, Muhamad Azamin, et al.
Published: (2019)
by: Anuar, Muhamad Azamin, et al.
Published: (2019)
The effect of intranasal administration of ACTH analogue toward neural progenitor/stem cells proliferation after traumatic brain injury
by: Loe, Michael Lumintang, et al.
Published: (2020)
by: Loe, Michael Lumintang, et al.
Published: (2020)
Lesion topography and microscopic white matter tract damage contribute to cognitive impairment in symptomatic carotid artery disease
by: Meng, Dewen, et al.
Published: (2017)
by: Meng, Dewen, et al.
Published: (2017)
The impact of 5-flurouracil on white matter tracts and possible protection by fluoxetine or indomethacin administration: in vivo and in vitro study
by: Al-Bayti, Ayoub Ali Hussein
Published: (2017)
by: Al-Bayti, Ayoub Ali Hussein
Published: (2017)
Intestinal piezo1 promotes neuroinflammation to facilitate oligodendrocyte ferroptosis post-traumatic brain injury
by: Jun, Ding Zhi, et al.
Published: (2024)
by: Jun, Ding Zhi, et al.
Published: (2024)
Case Studies of Non-CNS Drugs to Minimise Brain Penetration - Nonsedative Antihistamines
by: Crowe, Andrew
Published: (2015)
by: Crowe, Andrew
Published: (2015)
A fast spinning magnetic white dwarf in the double degenerate, super-Chandrasekhar system NLTT 12758
by: Kawka, Adéla, et al.
Published: (2017)
by: Kawka, Adéla, et al.
Published: (2017)
CX3CR1 reduces choline-deficient, ethionine-supplemented diet-induced liver injury and liver progenitor cell proliferation
by: Elsegood, C., et al.
Published: (2016)
by: Elsegood, C., et al.
Published: (2016)
Differential effects of 670 and 830 nm red near infrared irradiation therapy: A comparative study of optic nerve injury, retinal degeneration, traumatic brain and spinal cord injury
by: Giacci, M., et al.
Published: (2014)
by: Giacci, M., et al.
Published: (2014)
Invading macrophages play a major role in the liver progenitor cell response to chronic liver injury
by: Viebahn, C., et al.
Published: (2010)
by: Viebahn, C., et al.
Published: (2010)
Alterations in the microstructure of white matter in children and adolescents with Tourette syndrome measured using tract-based spatial statistics and probabilistic tractography
by: Sigurdsson, Hilmar P., et al.
Published: (2018)
by: Sigurdsson, Hilmar P., et al.
Published: (2018)
New insights into the pathology of white matter tracts in cerebral palsy from diffusion magnetic resonance imaging: A systematic review
by: Scheck, S., et al.
Published: (2012)
by: Scheck, S., et al.
Published: (2012)
Adrenomedullary progenitor cells: isolation and characterization of a multi-potent progenitor cell population
by: Vukicevic, Vladimir, et al.
Published: (2015)
by: Vukicevic, Vladimir, et al.
Published: (2015)
Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury
by: Köhn-Gaone, J., et al.
Published: (2016)
by: Köhn-Gaone, J., et al.
Published: (2016)
Three dimensional electron microscopy reveals changing axonal and myelin morphology along normal and partially injured optic nerves
by: Giacci, M., et al.
Published: (2018)
by: Giacci, M., et al.
Published: (2018)
Perfluorooctane sulfonate induces neuronal and oligodendrocytic differentiation in neural stem cells and alters the expression of PPARγ in vitro and in vivo
by: Wan Ibrahim, Wan Norhamidah, et al.
Published: (2013)
by: Wan Ibrahim, Wan Norhamidah, et al.
Published: (2013)
Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator activated receptor (PPAR) family member gamma, but not alpha or delta
by: Knight, B., et al.
Published: (2005)
by: Knight, B., et al.
Published: (2005)
The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs)
by: Rogers, H.A., et al.
Published: (2013)
by: Rogers, H.A., et al.
Published: (2013)
Similar Items
-
Oxidative stress in oligodendrocytes in the penumbra following partial injury to a CNS tract and its amelioration with 670nm light
by: Szymanski, C., et al.
Published: (2012) -
Myelin Sheath Decompaction, Axon Swelling, and Functional Loss during Chronic Secondary Degeneration in Rat Optic Nerve
by: Payne, S., et al.
Published: (2012) -
Life, death, and oxidative stress: fate mapping oligodendrocyte progenitor cells following neurotrauma
by: Giacci, M., et al.
Published: (2015) -
PROTECTING GLIA FROM OXIDATIVE STRESS DURING SECONDARY DEGENERATION FOLLOWING NEUROTRAUMA
by: Doig, R., et al.
Published: (2014) -
Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma
by: Savigni, D., et al.
Published: (2013)