Early Proliferation Does Not Prevent the Loss of Oligodendrocyte Progenitor Cells during the Chronic Phase of Secondary Degeneration in a CNS White Matter Tract

Partial injury to the central nervous system (CNS) is exacerbated by additional loss of neurons and glia via toxic events known as secondary degeneration. Using partial transection of the rat optic nerve (ON) as a model, we have previously shown that myelin decompaction persists during secondary deg...

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Bibliographic Details
Main Authors: Payne, S., Bartlett, C., Savigni, D., Harvey, A., Dunlop, S., Fitzgerald, Melinda
Format: Journal Article
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/20.500.11937/58953