Development of a Model for Functional Studies of ABCG2 (Breast Cancer Resistance Protein) Efflux Employing a Standard BeWo Clone (B24)
Human choriocarcinoma-derived BeWo cells express high levels of breast cancer resistance protein (BCRP/ABCG2) with no functional P-glycoprotein (P-gp) (ABCB1) activity, making them a potential model to study bidirectional ABCG2-mediated drug transport. However, the original BeWo clone (B24) availabl...
| Main Authors: | , |
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| Format: | Journal Article |
| Published: |
Mary Ann Liebert
2012
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/5886 |
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