Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - Experimental validation in human breast and colon cancer

Functional characterization of selective exosite-binding inhibitors of matrix metalloproteinase-13 (MMP-13) - Experimental validation in human breast and colon cancer

© 2016 Japan Society for Bioscience, Biotechnology, and Agrochemistry.Considering the pathological significance of MMP-13 in breast and colon cancers, exosite-based inhibition of the C-terminal hemopexin (Hpx) domain could serve as an alternative strategy to develop selective inhibitors for MMP-13....

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Bibliographic Details
Main Authors: Kothapalli, R., Siveen, K., Tan, T., Thiery, J., Kumar, A., Sethi, Gautam, Swaminathan, K.
Format: Journal Article
Published: 2016
Online Access:http://hdl.handle.net/20.500.11937/58851

Internet

http://hdl.handle.net/20.500.11937/58851

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