Tumour-infiltrating regulatory T cell density before neoadjuvant chemoradiotherapy for rectal cancer does not predict treatment response

Neoadjuvant (preoperative) chemoradiotherapy (CRT) decreases the risk of rectal cancer recurrence and reduces tumour volume prior to surgery. However, response to CRT varies considerably between individuals and factors associated with response are poorly understood. Foxp3 + regulatory T cells (Tregs...

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Bibliographic Details
Main Authors: McCoy, M., Hemmings, C., Anyaegbu, C., Austin, S., Lee-Pullen, T., Miller, T., Bulsara, M., Zeps, Nikolajs, Nowak, A., Lake, R., Platell, C.
Format: Journal Article
Published: Impact Journals LLC 2017
Online Access:http://hdl.handle.net/20.500.11937/58847