Enabling dual cellular destinations of polymeric nanoparticles for treatment following partial injury to the central nervous system

Following neurotrauma, oxidative stress is spread via the astrocytic syncytium and is associated with increased aquaporin 4 (AQP4), inflammatory cell infiltration, loss of neurons and glia and functional deficits. Herein we evaluate multimodal polymeric nanoparticles functionalized with an antibody...

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Bibliographic Details
Main Authors: Lozic, I., Hartz, R., Bartlett, C., Shaw, J., Archer, M., Naidu, P., Smith, N., Dunlop, S., Iyer, K., Kilburn, M., Fitzgerald, Melinda
Format: Journal Article
Published: Elsevier Ltd 2016
Online Access:http://hdl.handle.net/20.500.11937/58803