Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic Azithromycin

QR Code

Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic Azithromycin

Objective: Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured epithelial cells (epithelial to mesenchymal transition, EMT) may serve as a source of fibrosis. The macrolide antibiotic azithromyci...

Full description

Bibliographic Details
Main Authors:	Banerjee, B., Musk, M., Sutanto, E., Yerkovich, S., Hopkins, P., Knight, D., Lindsey-Temple, S., Stick, S., Kicic, Anthony, Chambers, D.
Format:	Journal Article
Published:	Public Library of Science 2012
Online Access:	http://hdl.handle.net/20.500.11937/58733

Similar Items

Azithromycin Inhibits Mesenchymal Transition of Allograft Epithelium
by: Banerjee, B., et al.
Published: (2011)

The airway epithelium is a direct source of matrix degrading enzymes in bronchiolitis obliterans syndrome
by: Banerjee, B., et al.
Published: (2011)

Azithromycin Mitigates Human Rhinovirus Impact On Epithelial Junctional Proteins And Barrier Function In Airway Epithelium
by: Looi, K., et al.
Published: (2017)

Circulating stem cells engraft the bronchial epithelium in humans after lung transplantation
by: May, L., et al.
Published: (2008)

Explaining the Bronchiolitis Obliterans Syndrome (BOS) Phenotype-Epithelial-Mesenchymal Transition (EMT) Occurs More Readily in Small Airway Epithelium
by: Banerjee, B., et al.
Published: (2010)

Posttransplant bronchiolitis obliterans syndrome is associated with bronchial epithelial to mesenchymal transition
by: Hodge, S., et al.
Published: (2009)

Cells of Epithelial Lineage Are Present in Blood, Engraft the Bronchial Epithelium, and Are Increased in Human Lung Transplantation
by: May, L.A., et al.
Published: (2009)

DYSREGULATED REPAIR AND EPITHELIAL INJURY IN SMALL AND LARGE AIRWAYS OF LUNG TRANSPLANT PATIENTS IS AMELIORATED BY AZITHROMYCIN
by: Kicic, Anthony, et al.
Published: (2014)

Where Do The Bronchioles Go? Epithelial-Mesenchymal Transition (EMT) Induction And Prevention In Epithelial Cells From Lung Transplant Patients
by: Banerjee, B., et al.
Published: (2011)

The differential effects of azithromycin on the airway epithelium in vitro and in vivo
by: Slater, Mariel, et al.
Published: (2016)

Epithelial Injury and Dysregulated Repair in Small and Large Airways of Lung Transplant Patients is Ameliorated by Azithromycin
by: Kicic, Anthony, et al.
Published: (2014)

Intrinsic biochemical and functional differences in bronchial epithelial cells of children with asthma
by: Kicic, Anthony, et al.
Published: (2006)

Bronchial brushings for investigating airway inflammation and remodelling
by: Looi, K., et al.
Published: (2011)

SUPPRESSION OF beta-CATENIN/CBP SIGNALING INHIBITS EPITHELIAL-MESENCHYMAL TRANSITION AND MIGRATION OF HUMAN AIRWAY EPITHELIUM
by: Moheimani, F., et al.
Published: (2015)

Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation
by: Clifford, Rachel L., et al.
Published: (2017)

The genetic and epigenetic landscapes of the epithelium in asthma
by: Moheimani, F., et al.
Published: (2016)

Epithelial Mesenchymal Transition (EMT) in Bronchiolitis Obliterans Syndrome (BOS) Is Not Restricted to Small Airways
by: Chambers, D.C., et al.
Published: (2009)

Novel insight into uPAR function in the bronchial epithelium in asthma using functional genomics
by: Bhaker, Sangita
Published: (2017)

METABOLOMIC RESPONSE OF HEALTHY AND CYSTIC FIBROSIS EPITHELIUM TO RHINOVIRUS
by: Agudelo-Romero, P., et al.
Published: (2019)

Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipients
by: Ling, K.M., et al.
Published: (2019)

Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium
by: Kicic, Anthony, et al.
Published: (2010)

Direct Evidence of Chronic Epithelial Injury and Dysregulated Repair in the Lung Allograft
by: Banerjee, B., et al.
Published: (2012)

Barrier Integrity Compromization As An Intrinsically Abnormal Process In Asthmatic Epithelium Independent Of Atopy
by: Looi, K., et al.
Published: (2011)

Characterization of side population cells from human airway epithelium
by: Hackett, T.L., et al.
Published: (2008)

TRANSCRIPTOME-PROFILES ASSOCIATED WITH ATOPIC ASTHMA DETECTABLE IN UPPER/LOWER AIRWAY EPITHELIUM
by: De Jong, E., et al.
Published: (2019)

Selection of housekeeping genes for real-time PCR in atopic human bronchial epithelial cells
by: He, J.Q., et al.
Published: (2008)

Successful establishment of primary small airway cell cultures in human lung transplantation
by: Banerjee, B., et al.
Published: (2009)

A transcriptomic comparison between nasal and bronchial airway epithelia from children
by: Stick, Stephen, et al.
Published: (2017)

Determinants of culture success in an airway epithelium sampling program of young children with cystic fibrosis
by: Garratt, L., et al.
Published: (2014)

Inhibition of P-glycoprotein - Mediated Efflux of Digoxinand Its Metabolites by Macrolide Antibiotics
by: Hughes, Jeffery, et al.
Published: (2010)

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability
by: Looi, K., et al.
Published: (2016)

TRANSCRIPTIONAL PROFILING OF EPITHELIUM REVEALS SIMILAR COMPOSITION, BUT PARTIALLY DIFFERING ORGANIZATION BETWEEN THE UPPER AND LOWER AIRWAY
by: De Jong, E., et al.
Published: (2018)

Intrinsic Differences Of Epithelial Tight Junctions In Asthmatic Airway Epithelium And Barrier Compromisation Following Human Rhinoviral Insult
by: Looi, K., et al.
Published: (2015)

Inducible NO synthase expression is low in airway epithelium from young children with cystic fibrosis
by: Moeller, A., et al.
Published: (2006)

Blockade of eosinophil-induced bronchial epithelial-mesenchymal transition with a geranyl acetophenone in a coculture model
by: Lee, Yu Zhao, et al.
Published: (2017)

The impact of azithromycin therapy on the airway microbiota in asthma
by: Slater, Mariel, et al.
Published: (2014)

Predicting response to Azithromycin therapy in asthma
by: Slater, Mariel
Published: (2015)

Bradycardia and hypothermia complicating azithromycin treatment
by: Benn, K., et al.
Published: (2017)

Pharmacokinetics of transfer of azithromycin into the breast milk of African mothers
by: Salman, S., et al.
Published: (2016)

Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma
by: Taylor, S.L., et al.
Published: (2019)