Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic Azithromycin

Objective: Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured epithelial cells (epithelial to mesenchymal transition, EMT) may serve as a source of fibrosis. The macrolide antibiotic azithromyci...

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Bibliographic Details
Main Authors: Banerjee, B., Musk, M., Sutanto, E., Yerkovich, S., Hopkins, P., Knight, D., Lindsey-Temple, S., Stick, S., Kicic, Anthony, Chambers, D.
Format: Journal Article
Published: Public Library of Science 2012
Online Access:http://hdl.handle.net/20.500.11937/58733