Murine mesothelioma induces locally-proliferating IL-10+TNF-a+CD206-CX3CR1+ M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy

© 2016 Taylor & Francis Group, LLC.We used a murine model to monitor changes to myeloid cell subsets, i.e., myeloid-derived suppressor cells (MDSCs), M1 macrophages that secrete pro-inflammatory cytokines and express CD40 and CD80 and suppressive M2 macrophages that secrete anti-inflammatory cyt...

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Bibliographic Details
Main Authors: Jackaman, Connie, Yeoh, T., Acuil, M., Gardner, Joanne, Nelson, Delia
Format: Journal Article
Published: Landes Bioscience 2016
Online Access:http://hdl.handle.net/20.500.11937/58466