Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors

© 2017 Elsevier Masson SAS Aberrant expression of lysine specific histone demethylase 1 (LSD1) has been increasingly associated with numerous cancer cells and several proof-of-concept studies are strongly suggestive of its potential as a druggable target. Tranylcypromine (TCP) is an antidepressant o...

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Bibliographic Details
Main Authors: Ji, Y., Lin, S., Wang, Y., Su, M., Zhang, W., Gunosewoyo, Hendra, Yang, F., Li, J., Tang, J., Zhou, Y., Yu, L.
Format: Journal Article
Published: Elsevier Masson 2017
Online Access:http://hdl.handle.net/20.500.11937/57745